Description

• Title:
  Boron Cluster Modification with Antiviral, Anticancer, and Modulation of Purinergic Receptors' Activities Based on the Nucleoside Structure
• Creator:
  Adamska-Bartlomiejczyk, Anna;
  Bednarska, Katarzyna;
  Bialek-Pietras, Magdalena;
  Kilianska, Zofia M;
  Mieczkowski, Adam;
  Olejniczak, Agnieszka B;
  Paradowska, Edyta;
  Studzinska, Miroslawa;
  Sulkowska, Zofia;
  Zolnierczyk, Jolanta D.;
  Leśnikowski, Zbigniew J
• Contributor:
  Hey-Hawkins, Evamarie;
  Vinas Teixidor, Clara
• Description:
  Nucleoside analogs have been in clinical use for several decades and have become cornerstones of treatment for patients with cancer or viral infections [1,2]. This is complemented with nucleoside antibiotics, a large family of microbial natural products and synthetic derivatives derived from nucleosides and nucleotides [3]. The approval of several new nucleoside drugs over the past decade demonstrates that this class of compounds still possesses strong potential [1,2]. The potential of nucleosides in chemotherapy is enhanced by development of new chemistries for nucleoside modification, better understanding of molecular mechanisms of nucleoside drugs’ actions [4], and pro‐drug technology [5,6]. One of the new developments in the medicinal chemistry of nucleosides is nucleoside derivatives comprising a boron component [7]. The boron part can contain a single boron atom [8] or several boron atoms in the form of a boron cluster (Figure 1.2.1) [9–11].
• Object availability:
  free access
• Date:
  2018.05.20
• Type:
  Book Section;
  PeerReviewed
• Publisher:
  Wiley
• Relation: http://eprints.ibb.waw.pl/1533 ;https://www.wiley.com/en-pl/Boron+Based+Compounds:+Potential+and+Emerging+Applications+in+Medicine-p-9781119275558
• Subject:
  RM Therapeutics. Pharmacology
• Identifier:
  Adamska-Bartlomiejczyk, Anna and Bednarska, Katarzyna and Bialek-Pietras, Magdalena and Kilianska, Zofia M and Mieczkowski, Adam and Olejniczak, Agnieszka B and Paradowska, Edyta and Studzinska, Miroslawa and Sulkowska, Zofia and Zolnierczyk, Jolanta D. and Leśnikowski, Zbigniew J (2018) Boron Cluster Modification with Antiviral, Anticancer, and Modulation of Purinergic Receptors' Activities Based on the Nucleoside Structure. In: Boron-Based Compounds Potential and Emerging Applications in Medicine. Wiley, pp. 20-34. ISBN 978-1-119-27555-8
• Data provider:
  Repozytorium Instytutu Biochemii i Biofizyki Polskiej Akademii Nauk
• Can I use it?:
  seek permission
• Type:
  text