Description

• Title:
  Functional and physical interactions of Faf1p, a Saccharomyces cerevisiae nucleolar protein.
• Creator:
  Karkusiewicz, Iwona;
  Rempola, Bozenna;
  Gromadka, Robert;
  Grynberg, Marcin;
  Rytka, Joanna
• Description:
  We report the discovery and characterisation of a novel nucleolar protein of Saccharomyces cerevisiae. We identified this protein encoded by ORF YIL019w, designated in SGD base as Faf1p, in a two hybrid interaction screen using the known nucleolar protein Krr1 as bait. The presented data indicate that depletion of the Faf1 protein has an impact on the 40S ribosomal subunit biogenesis resulting from a decrease in the production of 18S rRNA. The primary defect is apparently due to inefficient processing of 35S rRNA at the A(0), A(1), and A(2) cleavage sites.
• Object availability:
  free access
• Date:
  2004
• Type:
  Article;
  PeerReviewed
• Relation: http://eprints.ibb.waw.pl/36
• Subject:
  QR Microbiology
• Identifier:
  Karkusiewicz, Iwona and Rempola, Bozenna and Gromadka, Robert and Grynberg, Marcin and Rytka, Joanna (2004) Functional and physical interactions of Faf1p, a Saccharomyces cerevisiae nucleolar protein. Biochemical and biophysical research communications, 319 (2). pp. 349-57. ISSN 0006-291X
• Data provider:
  Repozytorium Instytutu Biochemii i Biofizyki Polskiej Akademii Nauk
• Can I use it?:
  seek permission
• Type:
  other