Description

• Title:
  The human Suv3 helicase interacts with replication protein A and flap endonuclease 1 in the nucleus
• Creator:
  Stępień, Piotr P.;
  Bohr, Vilhelm A;
  Kulikowicz, Tomasz
• Description:
  The human Suv3 helicase has been shown to be a major player in mitochondrial RNA surveillance and decay. In the present study we identify two new interaction partners of hSUV3: the RPA (replication protein A0 and FEN1 (flap endonuclease). Another single-strand-binding protein, mtSSB fails to affect hSUV3 activity. Flap endonuclease activity of FEN1 is stimulated by hSUV3 independenttly of flap length. SUV3 may play a significant role in nuclear DNA metabolism.
• Object availability:
  free access
• Date:
  2011
• Type:
  Article;
  PeerReviewed
• Language:
  English;
  eng
• Format:
  application/pdf
• Publisher:
  Biochemical Society
• Relation: http://eprints.ibb.waw.pl/234 ;http://www.biochemsoc.com ;
  10:1042/BJ201100991
• Subject:
  QH426 Genetics;
  QR Microbiology
• Identifier: http://eprints.ibb.waw.pl/234/1/BOHR_tekst_WORD.pdf ;
  Stępień, Piotr P. and Bohr, Vilhelm A and Kulikowicz, Tomasz (2011) The human Suv3 helicase interacts with replication protein A and flap endonuclease 1 in the nucleus. Biochemical Journal, 440 . pp. 293-300. ISSN 1042-0991
• Data provider:
  Repozytorium Instytutu Biochemii i Biofizyki Polskiej Akademii Nauk
• Can I use it?:
  seek permission
• Type:
  other